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Dr. Don Thomas, MD

I am Dr. Donald Thomas, MD, a rheumatologist treating hundreds of lupus patients for over 30 years. Read my first blog post here to understand why I started this website and blog about “The Lupus Encyclopedia” and “The Lupus Secrets”.

Dr. Don Thomas also enjoys educating and empowering doctors, medical students, nurses, physician assistants, nurse practitioners, and patients.

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Malar butterfly rash symptom of lupus

Types of Rash in Lupus: A Comprehensive Guide [March 2025 Update]

Lupus patients have many more types of rash than the commonly discussed butterfly rash and discoid lupus. After
blood vessels vascular with red blood cells floating inside an artery

Diabetes Drug Pioglitazone Helpful for Lupus [Suggests NIH study]

Lupus Research Article Peroxisome proliferator-activated receptor-γ agonist pioglitazone improves vascular and metabolic dysfunction in systemic lupus erythematosus This
Photo of a black woman getting a botox injection

Botox Injections and Lupus

If you have lupus and are considering Botox injections for cosmetic or medical purposes, it’s important to understand
News Flash COVID-19 vaccine for lupus patients

Covid-19 Vaccine for Lupus Patients: Please get your vaccine

Should We be Recommending the COVID-19 Vaccine for Lupus Patients?: Yes! What I tell my systemic lupus patients
Probiotic supplements and lupus

Lupus and Taking Probiotics/Prebiotics: The truth [Updated JUL ’23]

Lupus and taking probiotics: Should you take probiotics if you have lupus, and what are the best probiotics
VA disability for lupus

VA Disability for Lupus: Navigating Your Claim [Feb 2025 Update]

Startling statistic: A large study showed that Afghanistan and Iraqi veterans suffering from PTSD were twice as likely
Person with lupus spreading COVID-19 by not wearing a mask

Super spreader COVID-19: Infections surge big due to this [Updated]

Super spreader COVID-19: New study shows the answers in the Annals of Internal Medicine Wear a mask to
Sea moss along the coast

Sea Moss as a Lupus Prebiotic

Patients ask about Sea Moss as a Lupus Prebiotic: Sea moss was never on my radar until 2022-2023.
Image that says CAR-T Cells made simple

CAR-T Cell Therapy For Lupus Made Simple (January 2025 UPDATE)

The field of CAR-T therapies in treating autoimmune diseases like lupus is rapidly expanding. As of April 2024,
dry skin close up on the face of a woman

Lupus and Dry Skin

Lupus often manifests its effects on the skin. One potential problem is dry, itchy skin. Fortunately, a lot
Lupus and hives on arm

Lupus and Hives

Systemic lupus erythematosus (SLE) can cause hives (also called urticaria). Hives are itchy, swollen bumps that appear on
Type 1 interferon cytokines are inhibited by the anifrolumab FDA approval drug

Anifrolumab FDA Approval to Treat Systemic Lupus [Saphnelo February 2025 Update]

Anifrolumab (Saphnelo) is the 2nd FDA-approved biologic to treat systemic lupus erythematosus (SLE). The first biologic was belimumab
A lupus patient with Jaccoud

Lupus Tendonitis: A Common Cause of Pain in Lupus Patients

https://www.lupusencyclopedia.com/book-photos/#tendon…
Coronavirus vaccine for COVID-19 and lupus patients

COVID Vaccine for Immunocompromised Patients and What Drugs to Stop [December 2023 UPDATE]

The American College of Rheumatology Provides Guidance for stopping drugs to enhance the COVID vaccine for immunocompromised patients
Two thumbs up

FDA approves Benlysta for lupus nephritis December 2020

Benlysta (belimumab) is the 1st drug ever FDA-approved to treat lupus nephritis ​Historic milestone! ___________________________ NOTE: Johns Hopkins
Model of the kidney

What to Know about a Lupus Nephritis Urine Sample [UPDATED June 2024]

Lupus patients should provide a urine sample regularly to see if there is possible inflammation of the kidneys
Photo of person holding a soap bubble

The Best Soap for Lupus Patients (Feb 2025 Update)

Selecting the right soap for lupus patients is crucial because certain soaps can worsen irritation from cutaneous lupus
itchy skin like happens with lupus rashes

Itchy Skin Can Be a Sign of Active Lupus

Updated JUN 2023 Itchy skin can occur with active lupus rashes (cutaneous lupus). However, other causes are much
Woman with lupus helping lupus research for the Lupus Foundation of America

Share Lupus Experiences Now: Help current research on lupus

IF YOU HAVE LUPUS OR ARE A CAREGIVER: Help current research on lupus by sharing your experiences with
Vitamin D supplement preventing disease: How to prevent lupus

How to Prevent Lupus & Other Autoimmune Diseases [January 2025]

This blog post will give advice on how to prevent lupus and other autoimmune diseases. I will first
Text stating Mitochondria is the Powerhouse of the Cell a cause of fatigue in lupus

Fatigue in Lupus and Sjogren’s [March 2025 Update]

Fatigue is one of the most common and disabling symptoms affecting individuals living with systemic lupus erythematosus (SLE).
Lupus and gastro issues

Lupus and Gastro Issues [March 2025 Update]

Lupus and its treatments can affect the gastrointestinal (GI) tract, from the mouth to the intestines. Mouth sores
Microscopic view of a positive fluorescent antinuclear antibody test used to diagnose a lupus patient

Positive ANA workup – Is it lupus or not? [October 2024 Update]

Antinuclear antibodies (ANA) are present in up to 20% of the healthy population, depending upon the particular lab
Proteinuria in lupus nephritis. This is what a kidney looks like

Proteinuria in Lupus Nephritis: Video tips and the bottom line [March 2025 UPDATE]

When excessive protein leaks from the kidneys and into the urine, it is called proteinuria. Proteinuria in lupus
Dr. Don Thomas explains ANA negative lupus

Can You Have Lupus With a Negative ANA Test? “Yes you can!” (October 2024 Update)

Protect yourself from medical mistakes. A study by a large group of international lupus experts (Systemic Lupus International
Pregnant black woman's stomach with a fetus ultrasound at image for having a successful pregnancy with lupus

How to Have a Successful Pregnancy with Lupus [January 2025 Update)

A successful pregnancy is possible in most women who have systemic lupus erythematosus (SLE) with proper preparation and
Herbal supplements for lupus that worsen lupus

Supplements That Worsen Lupus & 6 That Help [March 2025 Update]

Lupus is an autoimmune disease where the immune system is overactive. This post discusses a 2024 research study
Woman who has a malar rash (butterfly rash) due to lupus with lupus disease activity

How Severe is Your Lupus? Use a Lupus Severity Index

Read on to learn how you to figure out your lupus disease activity with a Lupus Severity Index
Anti-SSA (anti-Ro) in a lupus patient

Anti-SSA Test (anti-Ro): Know Your Labs

Anti-SSA is a positive blood test in many lupus and Sjogren’s disease patients. It is also called anti-Ro
Low vitamin D levels can make lupus worse

The Best Lupus Books? Look in the useful list below

Kelli of “More Than Lupus” describes what she considers the best lupus books ​ What are your favorite
Lupus medication list with drug allergy list including sulfa and Bactrim antibiotics

Good Advice on Lupus and Bactrim [per sulfa antibiotic research]

Lupus and Bactrim: List sulfa antibiotics (like Bactrim) in your allergy list if you have lupus Lupus patients
New lupus test for lupus flares announced by The Lupus Foundation

The aiSLE DX Flare Risk Index Test: A new lupus lab test

The aiSLE DX Flare Risk Index test The Lupus Foundation of America, in its continuous quest to advocate
The Lupus Encyclopedia book cover 2nd edition

Three Potential Book Covers for The Lupus Encyclopedia 2nd Edition

THE VOTE IS IN! See the new book cover below 315 people voted for the new book cover
COVID Booster vaccine for lupus patients is possible according to research study

Immunosuppressed Patients Respond to Booster Shots: Hope for a COVID Booster Vaccine for Lupus and Other Autoimmune Disease Patients? [Updated 8/12/21]

  Will a COVID Booster Vaccine for Lupus Patients Increase Response Rates? We do not know, yet. However,
X-ray of respiratory system

Lupus and the Respiratory System [March 2025 Update]

The respiratory system, or the pulmonary system, is commonly affected by systemic lupus erythematosus (SLE). This system plays
COVID booster vaccine button

COVID Vaccines, Evusheld & Stopping Drugs for Shots [FEB 2023 Update]

  Stopping Methotrexate for 1 Week as Effective as 2 Weeks after Flu shots [FEB 2023 Update) This
smart phone with apps

Arthritis – “it’s a Pain in the App” [Coping with lupus]

Guest post: One method of coping with the struggles of lupus Living and coping with the challenges of
Immunosuppressants and COVID vaccine ACR guidelines and recommendations

Immunosuppressants and COVID Vaccine: Fundamentals in the new guidelines

Immunosuppressants and COVID vaccine: which you should stop and not stop American College of Rheumatology Clinical Guidance Summary UPDATED
Lupus life expectancy

Understanding Lupus Life Expectancy [Feb 2025 Update]

Dr. Thomas has systemic lupus erythematosus (SLE) patients in their 70s, 80s, and 90s! Living with lupus is
Lupus patient getting intravenous immunoglobulin

Intravenous Immunoglobulin: IVIG for Systemic Lupus Erythematosus

Immune globulins (also called immunoglobulins) are antibodies. A large number of antibodies given in IVIG for systemic lupus
The endocrine system and lupus

Lupus and The Endocrine System

Lupus, a complex autoimmune condition, impacts various systems in the body, including the endocrine system. The endocrine system
Drawing of an electron microscopic view of the hepatitis C virus

Lupus and Hepatitis C: Lupus Patients Should be Tested for Hepatitis C

The interactions of hepatitis C and systemic lupus is strange, and hepatitis C can mimic lupus … read
Lupus question should I get a 5th COVID vaccine and Evusheld

Do I need a 5th COVID Vaccine AND Evusheld if I have lupus? [December 2023 UPDATE]

December 2023 Update: Yearly Fall COVID shots and a replacement for Evusheld The coronavirus that causes COVID-19 has
Graphs showing Lupkynis voclosporin efficacy in lupus nephritis Lancet article

Voclosporin for Lupus Nephritis: Great results in The Lancet

Note the impressively higher response rates in the blue bars (Lupkynis + mycophenolate + steroids) compared to pink
Use of DHEA in lupus patients

DHEA and Lupus: Research shows it to be useful and good in some

Other Facts about DHEA and lupus – DHEA and lupus: DHEA stands for DeHydroEpiAndrosterone – It is produced
Childhood stress and lupus question answered by Dr. Donald Thomas

Childhood Trauma, PTSD, Racism, Stress, and Lupus

Multiple studies show that stress and trauma increase the risk of developing lupus as well as causing lupus
Woman sitting on chair

Spotlight on a Good Poem by Devoted Lupus Warrior

Lupus by Lupus Warrior and Lupus Fighter Shanelle Gabrielle “​I still have a purpose … A reason to
close-up photo of persons eye

Lupus and The Eyes

Lupus, or systemic lupus erythematosus (SLE), is a chronic autoimmune disease that can affect multiple organs and systems,
Asian woman doctor reading a chest x-ray showing pneumonia

New Pneumonia, Shingles, RSV, and Hepatitis Vaccine Recommendations [2024]

Centers for Disease Control 2024 Vaccine Recommendations In 2024 came out with its new vaccine recommendations. In this
Image showing complications of dry mouth from lupus exocrine involvement

Lupus and The Exocrine Gland System: Sjögren’s Disease [Mar ’25 Update]

Lupus patients can have dry mouth, eyes, and skin. Most of the time, this is due to having