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Research Studies in Lupus

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Dr. Don Thomas, MD

I am Dr. Donald Thomas, MD, a rheumatologist treating hundreds of lupus patients for over 30 years. Read my first blog post here to understand why I started this website and blog about “The Lupus Encyclopedia” and “The Lupus Secrets”.

Dr. Don Thomas also enjoys educating and empowering doctors, medical students, nurses, physician assistants, nurse practitioners, and patients.

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Lupus life expectancy

Understanding Lupus Life Expectancy [Feb 2025 Update]

Dr. Thomas has systemic lupus erythematosus (SLE) patients in their 70s, 80s, and 90s! Living with lupus is
Drawing of an electron microscopic view of the hepatitis C virus

Lupus and Hepatitis C: Lupus Patients Should be Tested for Hepatitis C

The interactions of hepatitis C and systemic lupus is strange, and hepatitis C can mimic lupus … read
Text stating Mitochondria is the Powerhouse of the Cell a cause of fatigue in lupus

Fatigue in Lupus and Sjogren’s [March 2025 Update]

Fatigue is one of the most common and disabling symptoms affecting individuals living with systemic lupus erythematosus (SLE).
The endocrine system and lupus

Lupus and The Endocrine System

Lupus, a complex autoimmune condition, impacts various systems in the body, including the endocrine system. The endocrine system
Stomach pain in lupus

Lupus Stomach Medications: Gastrointestinal Symptoms

Gastrointestinal (GI) symptoms and problems are common in lupus patients and can significantly impact their quality of life.
Malar butterfly rash symptom of lupus

How to Diagnose Lupus: 10 Symptoms (Feb 25 Update)

Diagnosing lupus is challenging, even for medical professionals. Early diagnosis is crucial for early treatment to reduce inflammation,
Dry cracked skin

Top Dermatologist Tips For Itchy, Dry Skin in Lupus and Sjögren’s [October 2024 Update]

Unfortunately, dry, itchy skin is a common problem in lupus patients. Most patients try everything they think may
A lupus patient with Jaccoud

Lupus Tendonitis: A Common Cause of Pain in Lupus Patients

https://www.lupusencyclopedia.com/book-photos/#tendon…
Coronavirus vaccine for COVID-19 and lupus patients

COVID Vaccine for Immunocompromised Patients and What Drugs to Stop [December 2023 UPDATE]

The American College of Rheumatology Provides Guidance for stopping drugs to enhance the COVID vaccine for immunocompromised patients
Hydroxychloroquine and Plaquenil Top Tips

Top Tips on Taking Hydroxychloroquine for Lupus [Ultimate Guide February 2025]

Taking hydroxychloroquine for systemic lupus erythematosus (SLE) is considered the most important drug for lupus. It is the
Connective Tissue Disease written on a white board by a doctor

Undifferentiated Connective Tissue Disease: It Is Real! (Feb 2025 Update)

Undifferentiated connective tissue disease (UCTD) is one of the most common diagnoses made by rheumatologists. Many systemic lupus
methotrexate for lupus bottle of methotrexate on label

Methotrexate for lupus: help it work better and prevent side effects [January 2025]

Methotrexate is one of the safest and most effective drugs for lupus. Since the 1980s, it has been
estrogen levels by age in women and lupus from puberty to menopause

Lupus in Women: From Puberty to Menopause

Lupus in women occurs much more often than in men. There are many reasons this occurs. Also, lupus
Anatomical drawing of a kidney with artery, vein, and ureter

Benlysta for lupus nephritis: Studies show it is effective

Hot off the press SEP 2020! The future is very bright for lupus treatments!     The future
Pregnant black woman's stomach with a fetus ultrasound at image for having a successful pregnancy with lupus

How to Have a Successful Pregnancy with Lupus [January 2025 Update)

A successful pregnancy is possible in most women who have systemic lupus erythematosus (SLE) with proper preparation and
Lennon Wall graffiti in Prague Czech Republic that says Lucy in the Sky with Diamonds

Lupus and “Lucy in the Sky with Diamonds”

What do the following have in common? Lupus A drawing by a 3-year-old Julian Lennon Flowers and gardening
Lupus Mottled Skin

Lupus Mottled Skin & Symptoms (Feb 2025 Update)

One skin issue associated with systemic lupus erythematosus (SLE) is “mottled skin,” with livedo reticularis being one of
X-ray of lupus joint and muscle pain

Lupus Joint and Muscle Pain [February 2025 Update]

Close to 90% of people with systemic lupus erythematosus (SLE) will have joint and muscle pain. Fortunately, today’s
Image of two kidneys and some doctors with the title chronic kidney disease

3 Ways to Stop Lupus Kidney Disease Progression [Jan 2025]

It is indeed possible to slow the progression of chronic kidney disease (CKD) in patients with lupus and
Pain from Fibromyalgia

Lupus and Fibromyalgia

Lupus and Fibromyalgia: Understanding the Connection Lupus and fibromyalgia are two distinct conditions, but they often coexist, causing
Lupus and the urinary system

Lupus and the Urinary System [March 2025 Update]

Kidney inflammation (lupus nephritis) occurs in around 45% of people who have systemic lupus erythematosus (SLE). Therefore, lupus
COVID Booster vaccine for lupus patients is possible according to research study

Immunosuppressed Patients Respond to Booster Shots: Hope for a COVID Booster Vaccine for Lupus and Other Autoimmune Disease Patients? [Updated 8/12/21]

  Will a COVID Booster Vaccine for Lupus Patients Increase Response Rates? We do not know, yet. However,
Herbal supplements for lupus that worsen lupus

Supplements That Worsen Lupus & 6 That Help [March 2025 Update]

Lupus is an autoimmune disease where the immune system is overactive. This post discusses a 2024 research study
Image of blood cells

Benlysta Reviews: Learn the amazing truth on how it works

  …
Two thumbs up

FDA approves Benlysta for lupus nephritis December 2020

Benlysta (belimumab) is the 1st drug ever FDA-approved to treat lupus nephritis ​Historic milestone! ___________________________ NOTE: Johns Hopkins
Dry mouth from lupus and Sjogren

Lupus Can Cause Tooth Decay: How to Prevent Dry Mouth and Cavities (February 2025 Update)

Did you know that lupus patients have a high rate of poor dental health and tend to lose
Anti-cardiolipin antibodies and lupus

Anticardiolipin Antibodies and Lupus [Feb 2025 Update]

Anticardiolipin antibodies (ACLA), a type of antiphospholipid antibody, can thicken the blood and potentially cause devastating blood clots
Illustration of collecting a urine sample

How to collect a urine sample properly for testing (UPDATED January 2025)

    It is essential for lupus patients to regularly collect an accurate clean catch urine sample  
Illustration of a clipboard, doctor and thyroid

Lupus and Thyroid Medications

Lupus and thyroid disease go hand in hand. The thyroid gland, which is situated at the front of
A man with trigger finger due to tenosynovitis

Now Research Shows: Lupus tendinitis, common cause of lupus pain

Jaccoud’s arthropathy due to lupus tendinitis (lupus tendonitis) and lupus tenosynovitis What is lupus tendinitis (also spelled lupus
Lupus related hair loss

Hair and Skin Problems in Lupus [Feb 2025 Update]

Most individuals with systemic lupus erythematosus (SLE) experience skin involvement or hair loss. There are many different types
Lupus and gastro issues

Lupus and Gastro Issues [March 2025 Update]

Lupus and its treatments can affect the gastrointestinal (GI) tract, from the mouth to the intestines. Mouth sores
Immunosuppressants and COVID vaccine ACR guidelines and recommendations

Immunosuppressants and COVID Vaccine: Fundamentals in the new guidelines

Immunosuppressants and COVID vaccine: which you should stop and not stop American College of Rheumatology Clinical Guidance Summary UPDATED
Arm wrestling to see which is better for lupus nephritis: Lupkynis or Benlysta

Lupkynis vs Benlysta for Lupus Nephritis: Dr. Thomas Has His Verdict!

Which is better for lupus nephritis? ​Here is my answer! Which is better for lupus nephritis? Benlysta or
VA disability for lupus

VA Disability for Lupus: Navigating Your Claim [Feb 2025 Update]

Startling statistic: A large study showed that Afghanistan and Iraqi veterans suffering from PTSD were twice as likely
Dr. Donald Thomas MD holding the new edition Lupus Encyclopedia A Comprehensive Guide for Patients and Health Care Providers

The Lupus Encyclopedia, edition 2: Now Available!

The Lupus Encyclopedia, edition 2: A Comprehensive Guide for Patients and Health Care Providers is now available at
A mask, needle, and syringe as symbols to protect from COVID-19

What is Evusheld and Who Should Get Evusheld: Prevent COVID-19 [OCT 2022 Update]

What is Evusheld? It is a treatment to prevent COVID-19 infections. It is not a vaccine. It is
Lupus patient in ICU hospital with COVID-19

COVID-19 deaths in rheumatic diseases

Research Shows More COVID-19 Deaths in Rheumatic Diseases: 10.5% of lupus and rheumatic disease patients died Much higher
Graphs showing Lupkynis voclosporin efficacy in lupus nephritis Lancet article

Voclosporin for Lupus Nephritis: Great results in The Lancet

Note the impressively higher response rates in the blue bars (Lupkynis + mycophenolate + steroids) compared to pink
Beat cancer woman with pink gloves and pink ribbon for breast cancer

Lupus and Cancer Risk: Learn to Prevent Cancer! [August 2024]

People who have lupus have an increased risk for getting some cancers. Knowing what they are and how
exercise and lupus photo of a woman on a stationary bicycle

Weight Loss & Exercise in Lupus: the science & patient view [March 2025 Update]

Weight loss & exercise provide many benefits to lupus patients. Healthcare providers consider exercise as “free medication” with
COVID booster vaccine button

COVID Vaccines, Evusheld & Stopping Drugs for Shots [FEB 2023 Update]

  Stopping Methotrexate for 1 Week as Effective as 2 Weeks after Flu shots [FEB 2023 Update) This
Managing Bone Health With Drugs

Managing Bone Health With Bisphosphonate Drugs

Individuals with systemic lupus erythematosus (SLE) are at increased risk of broken bones (fractures) due to osteoporosis. Increasing
Woman with Sjogren

Research Results in Dealing with Autoimmune Disease Fatigue Now

The causes of fatigue and dealing with autoimmune disease fatigue. ​ Tips on how to improve energy with
Lupus patient getting intravenous immunoglobulin

Intravenous Immunoglobulin: IVIG for Systemic Lupus Erythematosus

Immune globulins (also called immunoglobulins) are antibodies. A large number of antibodies given in IVIG for systemic lupus
Lupus headaches

Lupus Headaches: Causes, Symptoms, and Treatment [March 2025 Update]

Most systemic lupus erythematosus (SLE) patients get headaches. Are these due to lupus? Or are they due to
Lupus and the digestive system

Lupus and The Digestive System

Systemic lupus erythematosus (SLE), commonly known as lupus, is an autoimmune disorder that can affect nearly every organ
Discoid lupus erythematosus on the cheek of a white woman with systemic lupus

Can Discoid Lupus Turn into Systemic?- “Sure” Now more about the truth

The Latest Research Answers the Question: “Can discoid lupus turn into systemic lupus erythematosus?” Discoid lupus: note the
Person with lupus spreading COVID-19 by not wearing a mask

Super spreader COVID-19: Infections surge big due to this [Updated]

Super spreader COVID-19: New study shows the answers in the Annals of Internal Medicine Wear a mask to
Model of the kidney

What to Know about a Lupus Nephritis Urine Sample [UPDATED June 2024]

Lupus patients should provide a urine sample regularly to see if there is possible inflammation of the kidneys